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laterial Safety Data Sheet 4121100 9:00 AM MATERIALS TO AVOID (INCOMPATIBILITY): strong alkalies, oxyaen nitrogen peroxide, sodium, potassium, zinc, strong oxidizers, reactive metals (such as aluminum powders and magnesium powders), strong acids, amines, reducing agents, halogens or halogen compounds ` SECTION 11 • TOXICOLOGICAL INFORMATION Methylene chloride has been evaluated for possible cancer causing effects in laboratory animals. Inhalation studies at concentrations of 2,000 and +,000 ppm increased the incidence of malignant liver and lung tumors in mice. Three inhalation studies of rats have shown increased incidence of benign mammary gland tumors in female rats at concentrations of 500 ppm and above and increases in benign mammary -land tumors in males at concentrations of 1,00 ppm and above. Rats exposed to 50 and 200 ppm via inhalation showed no increased incidence of tumors. Mice and rats exposed by ingestion at levels up to 250 mg /kvrdav lifetime and hamsters exposed via inhalation to concentrations up to 3,00 ppm lifetime did not show and increased incidence of tumors. The International Agencv for Research on Cancer (LARC) has concluded that, with respect to methylene chloride, there is sufficient ev idence of the carcinogenicity to experimental animals and inadequate evidence of the carcinogenicity to humans, resulting in a classification as a 213 animal carcinogen. The NTP has identified methylene chloride as an animal carcinogen. Methylene chloride is listed on the I.ARC and NTP carcinogen lists but not by OSHA. The State of California has listed methylene chloride under Proposition 65 as a chemical known to the state to cause cancer. Epidemilogv studies of 751 humans chronically exposed to methylene chloride, in the workplace of which 252 were exposed for a minimum of 20 years did not demonstrate any increase in deaths caused by cancer or cardiac problems. A second study of 2,227 workers confirmed these results. Vandalism Remover Page 5 of 6 Reproductive toxicity tests have been conducted to evaluate the potential adverse effects methylene chloride may have on • reproduction and offspring of laboratory animals. The results indicate that methylene chloride does not cause birth defects in laboratory animals. Perchloroethvlene is listed as a potential carcinogen by IARC and INUP. Perchloroethylene has been shown to increase the incidence of tumors in certain strains of mice and rats. Other long -term inhalation studies in rats failed to show tumori genic response. Human data are limited and have not established an association between perchloroethy'lene exposure and cancer. Perehloroeth-'-lene is not believed to pose a measurable carcinogenic risk to man when handled as recommended. SECTION 12 ECOTOXICOLOGICAL INFORMATION ECOTOXICOLOGICAL INFORMATION: none known CHEMICAL FATE INFORMATION: none known BIODEGRADABILITY: none known SECTION 13 DISPOSAL CONSIDERATIONS Do not puncture or incinerate containers. When contents are depleted continue to depress button until all vas is expelled. Dispose of container in accordance with local, state, and federal regulations. SECTION 14 TRANSPORT INFORMATION • D.O.T. CLASSIFICATION: Consumer Commodity (Hazard Class ORk,'I -D) SECTION 15